Journal article

Do schizotypy dimensions reflect the symptoms of schizophrenia?

EHX Thomas, SL Rossell, EJ Tan, E Neill, TE Van Rheenen, SP Carruthers, PJ Sumner, S Louise, K Bozaoglu, C Gurvich

Australian and New Zealand Journal of Psychiatry | SAGE PUBLICATIONS LTD | Published : 2019

Abstract

Objective: The personality characteristics and symptoms observed in schizophrenia are postulated to lie on a continuum, with non-clinical manifestations referred to as schizotypy. High schizotypy behaviours are argued to correspond with the three main clusters of symptoms in schizophrenia: positive, negative and cognitive/disorganised symptoms, yet there is limited empirical evidence to support this. This study aimed to investigate whether schizotypy dimensions significantly correlate with their respective schizophrenia symptomatology in the largest sample to date. Methods: A total of 361 adults (103 patients with schizophrenia/schizoaffective disorder and 258 healthy controls) were assessed..

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Grants

Awarded by Jack Brockhoff Foundation


Funding Acknowledgements

This work was supported by a National Health and Medical Research council project grant (National Health and Medical Research Council [NHMRC] APP1060664 awarded to S.L.R.). E.H.X.T. was supported by an Australian Postgraduate Award at Monash University. T.E.V.R. was supported by a NHMRC Early Career Fellowship (APP1088785). T.E.V.R. receives grant funding unrelated to the current paper from the Jack Brockhoff Foundation, the University of Melbourne, the Barbara Dicker Brain Sciences Foundation, the Rebecca L Cooper Foundation and the Society of Mental Health Research (SMHR Australia). C.G. was supported by a NHMRC Early Career Fellowship (546262). S.L.R. and T.E.V.R. received funding from Australian Rotary Health/Bipolar Expedition and the Helen McPherson Smith Trust, which partly funded some of the healthy control data in this paper.